*MICHEL MEUNIER

Novel Non-Invasive Laser-Assisted Intraocular Drug Delivery System for an Efficient and Selective Gene Transfer Therapy

Challenge: Retinal degenerative diseases, such as age-related macular degeneration and glaucoma, are the leading causes of vision loss and affect tens of millions of individuals in the world. Emerging solutions with nucleic acids and therapeutic genes show promise. However, there remains a void in effective and non-invasive drug delivery systems for the back of the eye, which has hindered the … Read More

*SYLVAIN MARTEL

Magnetically Guided Bacteria to Specifically Deliver Anti-Cancer Agents to Colorectal Cancer Sites

Challenge: Many cancers are treated with cocktails of chemotherapeutic drugs designed to prevent growth and spread of cancerous cells. Chemotherapy damages healthy cells, causing undesired side effects such as myelosuppression and cardiotoxicity. Localized drug therapy, if appropriately delivered could have a major impact on quality of life and treatment efficacy. Solution: The lead investigator has pioneered a revolutionary drug delivery … Read More

DERRICK GIBBINGS

Drug delivery: silencing RNAs using exosomes

  Competition: EXPLORE Program 2014 Funding: $300,000 / 2 years Beginning: June 2015 Early research has shown that a new type of molecule called silencing RNAs could be readily designed to silence or inhibit virtually any gene in a very specific and powerful manner. This in turns eliminates the expression of the protein encoded by this gene. Because most diseases … Read More